Sisler cleared 5 feet, 11.25 inches, improving from her previous mark of 5 feet, 10.75 inches.
She cleared the same height as the winner, Neidra Covington of TCU, but earned seventh due to more misses.
Sisler will be the lone Mustang to advance to the championships.
Junior Jasmine Pickett failed to advance; she posted a 36th place finish in the triple jump. Pickett, who earned All-American honors last year in the triple jump, had a leap of 39 feet, 6 inches.
Pickett had her season best jump of 42 feet, 4 inches at the Big West Championships.
Senior Joe Gatel, the Big West Champion in the 10,000-meter run, failed to finish the 5,000-meter race Saturday evening.
Gatel entered the race with the with a season best time of 13:57.54, a time that would have won the qualifying race to advance to the NCAA Championships.
On Friday, sophomore Tenise Brewer just missed advancing to the quarterfinal in the 100 meter hurdles while six other Mustangs competed in the second day of competition.
Brewer finished 27th, running in the first heat of the women’s 100m hurdles, and finished with a time of 13.83. The top 24 advanced to Saturday’s quarterfinal with a time of 13.70 or better.
Tamika Robinson of Illinois posted the fastest time, 13.60, running in the third heat.
Brewer’s season best time of 13.79 was posted at the Mt. Sac. Relays.
The Mustangs had three athletes competing in the 3,000-meter steeplechase with senior Carl Dargitz posting the best finish at 21st. Dargitz finished with a time of 9:01.53, well off his season best of 8:49.29.
Senior Andy Wright finished 39th with a time of 9:13.62 while fellow senior Nathan Huerta came home 46th with a time of 9:35.51.
Also competing on Friday was freshman John Prader and sophomore Kyle Inks in the pole vault.
Pader finished 22nd when he matched his career-best 16 feet, 8.75 inches. Inks finished 32nd when he cleared 16 feet, 2.75 inches.
Three vaulters tied for first when they cleared 17 feet, 4.50 inches.
Freshman Taylor Herrera finished 35th in the 200 meter with a time of 21.55. Herrera missed in advancing to the quarterfinals with the top 24 advanced with a time of 21.29 or better.
On Thursday, sophomore Eric Suprenant and sophomore Daniel Erdman failed to move past the qualifying round in the first day of competition.
Suprenant posted a time of 53.67 in the 400m hurdles. Suprenant was the 41st qualifier in the meet.
Suprenant posted his career-best time, 52.02, at the Big West Conference Championships two weeks ago.
Erdman finished 16th in a field of 48. The sophomore posted a career-best mark of 55 feet, 9.75 inches. His pervious best of 55 feet, 9.25 inches was set on May 1.